Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Physiological Effect

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    401 result(s) found for: Physiological Effect. Displaying page 1 of 21.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2005-002475-32 Sponsor Protocol Number: 050526 FMS Start Date*: 2005-12-07
    Sponsor Name:Charitè Universitätmeditin Berlin
    Full Title: Pilotstudy about endocrinilogical, peripherphysilogical and painreducing effects of Gamma-hydroxybutyrate in combination with operant-behaviour-therapeutic paintherapy with patients in Fibromyalgia...
    Medical condition: Patients with Fibromyalgia-syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-000540-14 Sponsor Protocol Number: HIGHCARE Start Date*: 2008-05-20
    Sponsor Name:ISTITUTO AUXOLOGICO ITALIANO
    Full Title: Role of the renin-angiotensin system in the cardiovascular, metabolic, neurologic and respiratory response to hypobaric hypoxia during sustained exposure to high altitude.
    Medical condition: This study is aimed at the investigation of adaptative physiological mechanisms at high altitude and not at the development of new therapeutic indications.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 Cardiac disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001636-60 Sponsor Protocol Number: SL-3-2019 Start Date*: 2019-07-12
    Sponsor Name:University clinic of Nephrology and Hypertension, Regional Hospital Holstebro
    Full Title: The effect of spironolactone on renal hemodynamics in patients with essential hypertension
    Medical condition: Physiological responses in patients with essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-003367-40 Sponsor Protocol Number: 2007/049/HP Start Date*: 2009-03-03
    Sponsor Name:CHU de Rouen
    Full Title: Pilot study of the effect of a substance P antagonist, aprepitant, on aldosterone and cortisol secretions in healthy volunteers
    Medical condition: The aim is to measure plasma aldosterone and cortisol concentrations in basal conditions and in response to different stimulation tests of the adrenal function
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002726-32 Sponsor Protocol Number: 65/2006/U/Sper Start Date*: 2006-06-20
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: PROtection of coronary Microcirculation by Iloprost: Safety and Efficacy evaluation in PCI
    Medical condition: coronary angioplasty
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050329 Coronary angioplasty LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2022-002137-34 Sponsor Protocol Number: SVS.FAM.01 Start Date*: 2022-07-25
    Sponsor Name:Hospital of South West Jutland
    Full Title: Rapid infusion of Ringer's lactate solution at different temperatures and the effects on circulation and perfusion in healthy volunteers – a randomized crossover trial
    Medical condition: Hemodynamic parameters is to be investigated -- comparing cold fluids to body temperature fluids.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010614-30 Sponsor Protocol Number: CH/2007/2746 Start Date*: 2009-05-08
    Sponsor Name:University Hospitals Bristol
    Full Title: Randomised cross-over pilot study to determine the effects of isoflurane and propofol on pulmonary vascular resistance in children with pulmoanry hypertension
    Medical condition: children with pulmonary hypertension
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2006-000837-36 Sponsor Protocol Number: 20060123 Start Date*: 2006-06-07
    Sponsor Name:Beroendecentrum Stockholm
    Full Title: Effect of Naltrexone on cue-induced craving for Amphetamine in amphetamine dependent individuals
    Medical condition: Amphetamine dependence
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000213-33 Sponsor Protocol Number: 14012020 Start Date*: 2020-04-21
    Sponsor Name:Department of Dentistry and Oral Health
    Full Title: Fluoride in saliva during and after use of high-fluoride toothpaste
    Medical condition: Not applicable. A physiological phenomena is explored.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004848 10053349 Pharmacokinetic study LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-004560-21 Sponsor Protocol Number: NL_ABR-43379 Start Date*: 2013-04-03
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: The effect of ticagrelor on the adenosine system
    Medical condition: We will study in healthy volunteers the effect of ticagrelor on the vasodilator effect of dipyridamole
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2015-002538-32 Sponsor Protocol Number: MY-1-2015 Start Date*: 2015-10-26
    Sponsor Name:Medicinsk Forskningsafsnit, Regionshospitalet Holstebro (Department of Medical Research, Regional Hospital Holstebro)
    Full Title: THE EFFECT OF ACYL-GHRELIN ON SODIUM REABSORPTION VIA ENAC IN HEALTHY VOLUNTEERS IN A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, CROSS-OVER STUDY
    Medical condition: The physiological responses to Acyl-ghrelin-injection on the sodium reabsorption via ENaC in healthy subjects.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-004411-53 Sponsor Protocol Number: Erythromycin_v5 Start Date*: 2014-05-15
    Sponsor Name:University of Leuven
    Full Title: Brain mechanisms underlying the effect of the motilin receptor agonist erythromycin on hunger in normal weight subjects
    Medical condition: The effect of erythromycin administration on hunger and brain responses will be tested in healthy volunteers
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002349-30 Sponsor Protocol Number: cod2017 Start Date*: 2017-09-12
    Sponsor Name:TARGID, KU Leuven
    Full Title: Effect of codeine on pharyngeal and esophageal motility in healthy subjects: a double-blind, placebo-controlled, randomized, cross-over study
    Medical condition: we will investigate the effect of codeine on motility in the pharynx and esophagus in healthy subjects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-004946-41 Sponsor Protocol Number: s57223 Start Date*: 2014-11-19
    Sponsor Name:KULeuven
    Full Title: The influence of GLP-1 analog, liraglutide, on gastric accommodation, gastric emptying, hunger and the migrating motor complex in healthy volunteers
    Medical condition: healthy volunteers no medical condition; drug will be studied because it is known to influence gastric motility
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-000594-81 Sponsor Protocol Number: S65020 Start Date*: 2021-05-07
    Sponsor Name:University Hospitals Leuven (UZ Leuven)
    Full Title: The effect of corticotropin release hormone on duodenal markers and gastric sensorimotor function in healthy volunteers
    Medical condition: To assess the effect of the CRH on duodenal mast cell count, eosinophil count, immune activation, mucosal permeability and gastric sensorimotor function and gastrointestinal symptoms.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003404-39 Sponsor Protocol Number: JBR-2-2013 Start Date*: 2014-01-03
    Sponsor Name:Department of Medical Research, Regional Hospital Holstebro
    Full Title: The effect of sodium nitrite infusion on renal variables, brachial and central blood pressure during enzyme inhibition by allopurinol, enalapril or acetazolamid in healthy subjects. A randomized, d...
    Medical condition: The normal physiological responses in healthy subjects
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018640-13 Sponsor Protocol Number: DERMOPED_001_DA_ISS Start Date*: 2009-10-28
    Sponsor Name:GUNA S.P.A.
    Full Title: "Evaluation of Clinical Immunology of a long-term treatment with Physiological Regulating Medicine in a Pediatric Population suffering from chronic atopic dermatitis. Experimental study randomized ...
    Medical condition: Atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004870 10013289 Disorders involving the immune mechanism LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003131-38 Sponsor Protocol Number: DOPA2016 Start Date*: 2017-06-23
    Sponsor Name:TARGID, KU Leuven
    Full Title: The effect of chlorpromazine (Largactil), a dopamine type 2-(D2-) receptor antagonist, on esophageal sensitivity in healthy volunteers: a randomized, double-blind, placebo-controlled study
    Medical condition: Increased esophageal sensitivity in refractory gastro-esophageal reflux disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002239-33 Sponsor Protocol Number: CRHMOT2014 Start Date*: 2014-10-14
    Sponsor Name:TARGID, KU Leuven
    Full Title: The effect of corticotrophin-releasing hormone (CRH) on esophageal motility in healthy volunteers
    Medical condition: Changes in esophageal motility induced by CRH-administration
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-000563-16 Sponsor Protocol Number: Citalopram2016 Start Date*: 2016-06-09
    Sponsor Name:K.U. Leuven
    Full Title: Effect of citalopram on fasting and postprandial lower esophageal sphincter function in healthy subjects: a double-blind, placebo-controlled, randomized, cross-over study
    Medical condition: Increased lower esophageal sphincter pressure
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Mon May 20 01:31:28 CEST 2024 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA